Composite

Part:BBa_K5238005:Design

Designed by: Yishi Jia   Group: iGEM24_NJMU-CHINA   (2024-07-10)


produce tetrahydrofolate to bind to target lilrb3 for the treatment of Alzheimer's disease


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 972
    Illegal EcoRI site found at 1115
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 972
    Illegal EcoRI site found at 1115
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 972
    Illegal EcoRI site found at 1115
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 972
    Illegal EcoRI site found at 1115
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal EcoRI site found at 972
    Illegal EcoRI site found at 1115
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 997


Design Notes

folK https://www.ncbi.nlm.nih.gov/gene/15552891 folE https://www.ncbi.nlm.nih.gov/gene/77216393


Source

References: 1. Zhang, S.-M., et al. (2002). Folate, vitamin B6, and vitamin B12 intakes in relation to risk of stroke among men. *Stroke*, 33(1), 196-202. 2. Reynolds, E. (2006). Vitamin B12, folic acid, and the nervous system. *The Lancet Neurology*, 5(11), 949-960.


References